Does early goal directed therapy in sepsis still hold relevance in low and middle-income countries?
Keywords:
Early goal directed therapy, EGDT, low and middle income countries, SepsisAbstract
Abstract
The efficacy of early goal directed therapy in improving outcomes has been questioned in few recent studies. But, does that hold true for low and middle income countries like Nepal? This editorial expresses the views of the editors on the usual care of sepsis patients and early goal directed therapy in resource limited settings.
References
2. Levy MM, Dellinger RP, Townsend SR, Linde-Zwirble WT, Marshall JC, Bion J, et al. Surviving Sepsis Campaign.The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Crit Care Med 2010;38:367-74.https://doi.org/10.1097/CCM.0b013e3181cb0cdc [PMid:20035219]
3. Angus DC1, Barnato AE, Bell D, Bellomo R, Chong CR, Coats TJ, et al. A systematic review and meta-analysis of early goal-directed therapy for septic shock: the ARISE, ProCESS and ProMISe Investigators. Intensive Care Med 2015;41:1549-60. https://doi.org/10.1007/s00134-015-3822-1 [PMid:25952825]
4. S Koirala, A Ghimire, A Sharma, B Bhattarai. ICU admission and outcomes in a community-based tertiary care hospital: an audit of one year. Health Renaissance 2011;9:83-7. https://doi.org/10.3126/hren.v9i2.4978
5. Phua J, Koh Y, Du B, Tang YQ, Divatia JV, Tan CC, et al. Management of severe sepsis in patients admitted to Asian intensive care units: prospective cohort study. BMJ 2011342:d3245. https://doi.org/10.1136/bmj.d3245
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